Modelling and treating Hirschsprung disease: stem cells to the rescue?
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چکیده
منابع مشابه
Surgical Intervention to Rescue Hirschsprung Disease in a Rat Model
BACKGROUND/AIMS Rats with a spontaneous null mutation in endothelin receptor type B or Ednrb (sl/sl; spotting lethal) lack enteric neurons in the distal bowel and usually die within the first week after birth. This early postnatal lethality limits their use for examining the potential of cell therapy to treat Hirschsprung disease, and for studies of the influence of EDNRB on the mature CNS and ...
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ژورنال
عنوان ژورنال: Nature Reviews Gastroenterology & Hepatology
سال: 2016
ISSN: 1759-5045,1759-5053
DOI: 10.1038/nrgastro.2016.34